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Assay Detail

CHEMBL4624338

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of NF-kappaB p65 in human HeLa cells nuclear extract by chemiluminescent assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HeLa
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Transcription factor p65 (CHEMBL5533)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Antiproliferative Flavanoid Dimers Isolated from Brazilian Red Propolis.
Banzato TP, Gubiani JR, Bernardi DI, Nogueira CR, Monteiro AF, Juliano FF, de Alencar SM, Pilli RA, Lima CA, Longato GB, Ferreira AG, Foglio MA, Carvalho JE, Vendramini-Costa DB, Berlinck RGS.
J Nat Prod (2020) 83 : 1784 -1793
PubMed 32525315 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.22 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4649115 1 8.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4649115 IC50 = 6.0 nM 8.22