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Assay Detail

CHEMBL4624341

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Functional
Cytotoxicity against human HT-29 cells after 3 days by sulforhodamine B assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 1 — Organism
Curated By Autocuration

Target

HT-29 (CHEMBL384)
Type CELL-LINE
Organism Homo sapiens

Publication

Antiproliferative Flavanoid Dimers Isolated from Brazilian Red Propolis.
Banzato TP, Gubiani JR, Bernardi DI, Nogueira CR, Monteiro AF, Juliano FF, de Alencar SM, Pilli RA, Lima CA, Longato GB, Ferreira AG, Foglio MA, Carvalho JE, Vendramini-Costa DB, Berlinck RGS.
J Nat Prod (2020) 83 : 1784 -1793
PubMed 32525315 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4649115 1 5.80
CHEMBL4646604 1 5.80
CHEMBL4638161 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4649115 IC50 = 1600.0 nM 5.80
CHEMBL4646604 IC50 = 1600.0 nM 5.80
CHEMBL4638161 IC50 = 1600.0 nM 5.80