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Assay Detail

CHEMBL4624359

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Saccharomyces cerevisiae alpha-glucosidase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

3,4-Dihydroxyphenethyl nitrate with nitric oxide releasing, antioxidant, hypoglycemic and hypolipidemic effects.
Xie YD, Liu JP, Wang W, Shi YH, Wang XP, Sun M, Xu XY, Li N.
Bioorg Med Chem Lett (2020) 30 : 127277 -127277
PubMed 32527456 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.63 4.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4644322 1 4.74
CHEMBL1950045 HYDROXYTYROSOL 3.0 1 4.51
CHEMBL404271 ACARBOSE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4644322 IC50 = 18020.0 nM 4.74
CHEMBL1950045 HYDROXYTYROSOL IC50 = 30710.0 nM 4.51
CHEMBL404271 ACARBOSE IC50 = 232000.0 nM -