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Assay Detail

CHEMBL4624393

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antifungal activity against Saccharomyces cerevisiae AD18 assessed as fungal growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Saccharomyces cerevisiae
Confidence 1 — Organism
Curated By Autocuration

Target

Saccharomyces cerevisiae (CHEMBL361)
Type ORGANISM
Organism Saccharomyces cerevisiae

Publication

An effective method to produce 7-epitaxol from taxol in HCO<sub>3</sub><sup>.</sup>
Liu Y, Ma X, Zhou M, Hao X, Zhu X.
Bioorg Med Chem Lett (2020) 30 : 127285 -127285
PubMed 32527458 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.15 4.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL503883 1 4.15
CHEMBL428647 PACLITAXEL 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL503883 IC50 = 71500.0 nM 4.15
CHEMBL428647 PACLITAXEL IC50 > 100000.0 nM -