Assay Detail
Binding
CHEMBL4625426
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Non-competitive mixed inhibition of Yersinia enterocolitica YopH assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Yersinia enterocolitica |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase YopH (CHEMBL4404) ↗| Type | SINGLE PROTEIN |
| Organism | Yersinia enterocolitica |
Publication
A chalcone derivative binds a putative allosteric site of YopH: Inhibition of a virulence factor of Yersinia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.17 | 4.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL282731 | CICHORIC ACID | — | 1 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL282731 | CICHORIC ACID | Ki | = | 68300.0 | nM | 4.17 |