Assay Detail
Binding
CHEMBL4627152
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Inhibition of bovine chymotrypsin using flurogenic substrate as chymotrypsin substrate 2 by fluorescence assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.41 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4637939 | — | — | 1 | 6.34 |
| CHEMBL4559386 | — | — | 1 | 6.16 |
| CHEMBL4641674 | — | — | 1 | 5.85 |
| CHEMBL4635621 | — | — | 1 | 5.13 |
| CHEMBL4638075 | — | — | 1 | 4.89 |
| CHEMBL4640892 | — | — | 1 | 4.84 |
| CHEMBL4635434 | — | — | 1 | 4.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4637939 | — | Ki | = | 460.0 | nM | 6.34 |
| CHEMBL4559386 | — | Ki | = | 690.0 | nM | 6.16 |
| CHEMBL4641674 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL4635621 | — | Ki | = | 7420.0 | nM | 5.13 |
| CHEMBL4638075 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL4640892 | — | Ki | = | 14500.0 | nM | 4.84 |
| CHEMBL4635434 | — | Ki | = | 21600.0 | nM | 4.67 |