Assay Detail
ADMET
CHEMBL4627595
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HeLa cells assessed as inhibition of cell viability incubated for 24 hrs by resazurin dye based fluorescence analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of bis-N<sup>2</sup>,N<sup>2</sup>'-(4-hydroxycoumarin-3-yl)ethylidene]-2,3-dihydroxysuccinodihydrazides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.89 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50588 | EMETINE | 4.0 | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50588 | EMETINE | IC50 | = | 13.0 | nM | 7.89 |