Assay Detail
Binding
CHEMBL4627716
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Inhibition of JAK2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.55 | 9.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4634979 | — | — | 1 | 9.60 |
| CHEMBL4635876 | — | — | 1 | 9.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4634979 | — | IC50 | = | 0.2512 | nM | 9.60 |
| CHEMBL4635876 | — | IC50 | = | 0.3162 | nM | 9.50 |