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Assay Detail

CHEMBL4628401

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Binding
Inhibition of alpha-glucosidase (unknown origin) using p-NPG as substrate by Dixon plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Tetra-aryl cyclobutane and stilbenes from the rhizomes of Rheum undulatum and their α-glucosidase inhibitory activity: Biological evaluation, kinetic analysis, and molecular docking simulation.
Ha MT, Kim M, Kim CS, Park SE, Kim JA, Woo MH, Choi JS, Min BS.
Bioorg Med Chem Lett (2020) 30 : 127049 -127049
PubMed 32111435 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.61 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4646818 1 6.40
CHEMBL113029 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4646818 Ki = 400.0 nM 6.40
CHEMBL113029 Ki = 15300.0 nM 4.82