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Assay Detail

CHEMBL4629157

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as copper-chelating scavenging activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone.
Bailly C, Hecquet PE, Kouach M, Thuru X, Goossens JF.
Bioorg Med Chem (2020) 28 : 115463 -115463
PubMed 32241621 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.29 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL223155 1 5.52
CHEMBL290916 EDARAVONE 4.0 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL223155 IC50 = 3000.0 nM 5.52
CHEMBL290916 EDARAVONE IC50 = 9000.0 nM 5.05