Assay Detail
Binding
CHEMBL4650001
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Alphascreen assay. Binding to FALZA (domain start/stop: S2791-H2911) by alphascreen assay
1
Total Activities
1
Compounds Tested
1
Activity Types
4
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Category | Alphascreen assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Nucleosome-remodeling factor subunit BPTF (CHEMBL3085621) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
EUbOPEN bromodomain assay panel
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.83 | 5.83 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Peptide | Peptide | - | — | SGRGK(ac)GGK(ac)GLGK(ac)GGAK(ac)RHRK(biotin)-acid |
| Protein Sequence | Protein Sequence | - | — | MHHHHHHSSGVDLGTENLYFQSMSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSH |
| Refseq Start/Stop | Refseq Start/Stop | - | — | S2791-H2911 |
| Target UniProt Accession | Target UniProt Accession | - | — | Q12830 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3785432 | — | — | 1 | 5.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3785432 | — | IC50 | = | 1461.0 | nM | 5.83 |