Assay Detail
ADMET
CHEMBL4666235
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against rat LA7 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Cell Type | LA7 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.92 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4785995 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4785995 | — | IC50 | = | 12050.0 | nM | 4.92 |