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Assay Detail

CHEMBL4667661

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore.
Ahn S,Kim J,An S,Pyo JJ,Jung D,Lee J,Hwang SY,Gong J,Shin I,Kim HP,Kim H,Noh M
Bioorg Med Chem (2019) 27 : 2948 -2958
PubMed 31128991 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.26 4.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4746258 1 4.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4746258 IC50 = 55500.0 nM 4.26