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Assay Detail

CHEMBL4667823

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against drug-resistant human KB/VCR cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KB
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Design, synthesis, and biological activity evaluation of (-)-6-O-desmethylantofine analogues as potent anti-cancer agents.
Han G,Qing L,Wu M,Wang Y,Liu Y,Liu X,Wang Z,Ding J,Meng LH,Wang Q
Bioorg Med Chem (2019) 27 : 3070 -3081
PubMed 31171403 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.22 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2289201 1 6.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2289201 IC50 = 600.0 nM 6.22