Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4668012

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Mixed inhibition of recombinant Trypanosoma brucei rhodesain expressed in Pichia pastoris by Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma brucei
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Rhodesain (CHEMBL4188)
Type SINGLE PROTEIN
Organism Trypanosoma brucei rhodesiense

Publication

Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.
Pereira GAN,da Silva EB,Braga SFP,Leite PG,Martins LC,Vieira RP,Soh WT,Villela FS,Costa FMR,Ray D,de Andrade SF,Brandstetter H,Oliveira RB,Caffrey CR,Machado FS,Ferreira RS
Eur J Med Chem (2019) 179 : 765 -778
PubMed 31284086 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL531738 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL531738 Ki = 10000.0 nM 5.00