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Assay Detail

CHEMBL4668378

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DNA topoisomerase2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Colchicine Alkaloids and Synthetic Analogues: Current Progress and Perspectives.
Gracheva IA,Shchegravina ES,Schmalz HG,Beletskaya IP,Fedorov AY
J Med Chem (2020) 63 : 10618 -10651
PubMed 32432867 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.05 5.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL61609 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL61609 IC50 = 9000.0 nM 5.05