Assay Detail
Functional
CHEMBL4668394
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Antiproliferative activity against human A549 cells incubated for 36 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Colchicine Alkaloids and Synthetic Analogues: Current Progress and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.79 | 7.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18981 | THIOCOLCHICINE | — | 1 | 7.14 |
| CHEMBL153052 | — | — | 1 | 6.62 |
| CHEMBL153629 | — | — | 1 | 6.60 |
| CHEMBL357350 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18981 | THIOCOLCHICINE | IC50 | = | 72.0 | nM | 7.14 |
| CHEMBL153052 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL153629 | — | IC50 | = | 252.0 | nM | 6.60 |
| CHEMBL357350 | — | IC50 | = | 0.001 | nM | - |