Assay Detail
Functional
CHEMBL4668397
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Antiproliferative activity against human TE-671 cells incubated for 36 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | TE-671 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Colchicine Alkaloids and Synthetic Analogues: Current Progress and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.86 | 10.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18981 | THIOCOLCHICINE | — | 1 | 10.62 |
| CHEMBL153629 | — | — | 1 | 10.08 |
| CHEMBL153052 | — | — | 1 | 5.88 |
| CHEMBL357350 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18981 | THIOCOLCHICINE | IC50 | = | 0.024 | nM | 10.62 |
| CHEMBL153629 | — | IC50 | = | 0.084 | nM | 10.08 |
| CHEMBL153052 | — | IC50 | = | 1320.0 | nM | 5.88 |
| CHEMBL357350 | — | IC50 | = | 0.001 | nM | - |