Assay Detail
Functional
CHEMBL4668413
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Antiproliferative activity against human PANC1 cells incubated for 72 hrs by WST assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Colchicine Alkaloids and Synthetic Analogues: Current Progress and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.68 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1985898 | — | — | 1 | 7.10 |
| CHEMBL486504 | N-ACETYLCOLCHINOL | -1.0 | 1 | 5.36 |
| CHEMBL4789261 | — | — | 1 | 5.16 |
| CHEMBL4763986 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1985898 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL486504 | N-ACETYLCOLCHINOL | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL4789261 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL4763986 | — | IC50 | = | 7900.0 | nM | 5.10 |