Assay Detail
Binding
CHEMBL4668571
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Inhibition of C5 complement protein in 2% human serum incubated for 15 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Serum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Ocular Disease Therapeutics: Design and Delivery of Drugs for Diseases of the Eye.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.42 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2203296 | — | — | 1 | 6.68 |
| CHEMBL2204196 | — | — | 1 | 6.36 |
| CHEMBL4756677 | — | — | 1 | 6.21 |
| CHEMBL4757748 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2203296 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL2204196 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL4756677 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL4757748 | — | IC50 | <= | 5.0 | nM | - |