Assay Detail
Binding
CHEMBL4668610
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human MMP3 catalytic domain (81 to 256 residues) expressed in Escherichia coli BL21 (DE3) pLysS by 15N-HSQC-NMR spectroscopy
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fragment Linking Strategies for Structure-Based Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 3.55 | 3.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL73380 | — | — | 1 | 3.55 |
| CHEMBL734 | ACETOHYDROXAMIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL73380 | — | Kd | = | 280000.0 | nM | 3.55 |
| CHEMBL734 | ACETOHYDROXAMIC ACID | Kd | = | 17000000.0 | nM | - |