Assay Detail
ADMET
CHEMBL4668992
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Cytotoxicity against human HepG2 cells after 3 days by microplate reader analysis
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Generation of Stilbene Antimicrobials against Multiresistant Strains of Staphylococcus aureus through Biotransformation by the Enzymatic Secretome of Botrytis cinerea.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 4.73 | 5.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.93 |
| CHEMBL4762690 | — | — | 1 | 4.82 |
| CHEMBL4790057 | — | — | 1 | 4.72 |
| CHEMBL4795777 | — | — | 1 | 4.66 |
| CHEMBL4796158 | — | — | 1 | 4.64 |
| CHEMBL4790531 | — | — | 1 | 4.57 |
| CHEMBL4781017 | — | — | 1 | 4.57 |
| CHEMBL4743922 | — | — | 1 | 4.54 |
| CHEMBL4559942 | — | — | 1 | 4.54 |
| CHEMBL518935 | — | — | 1 | 4.32 |
| CHEMBL4799520 | — | — | 1 | - |
| CHEMBL4746785 | — | — | 1 | - |
| CHEMBL4783196 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 1180.0 | nM | 5.93 |
| CHEMBL4762690 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL4790057 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL4795777 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL4796158 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL4790531 | — | IC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL4781017 | — | IC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL4743922 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL4559942 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL518935 | — | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL4799520 | — | IC50 | - | — | - | |
| CHEMBL4746785 | — | IC50 | - | — | - | |
| CHEMBL4783196 | — | IC50 | > | 95000.0 | nM | - |