Assay Detail
Functional
CHEMBL4671336
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplasmodial activity against synchronous gametocyte early stage of Plasmodium falciparum 3D7 harboring luc7 incubated for 72 hrs by ONE-Glo luciferase assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, Structure-Activity Relationship, and Antimalarial Efficacy of 6-Chloro-2-arylvinylquinolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.70 | 7.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL307261 | ARTENIMOL | 3.0 | 1 | 7.76 |
| CHEMBL405110 | METHYLENE BLUE ANHYDROUS | 4.0 | 1 | 7.13 |
| CHEMBL4758877 | — | — | 1 | 6.33 |
| CHEMBL4751906 | — | — | 1 | 6.23 |
| CHEMBL4792510 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL307261 | ARTENIMOL | EC50 | = | 17.4 | nM | 7.76 |
| CHEMBL405110 | METHYLENE BLUE ANHYDROUS | EC50 | = | 74.7 | nM | 7.13 |
| CHEMBL4758877 | — | EC50 | = | 471.5 | nM | 6.33 |
| CHEMBL4751906 | — | EC50 | = | 590.7 | nM | 6.23 |
| CHEMBL4792510 | — | EC50 | = | 909.9 | nM | 6.04 |