Assay Detail
Binding
CHEMBL4671535
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at FPR in Wistar rat assessed as inhibition of PGF2alpha-induced uterus contraction
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Uterus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Prostaglandin F2-alpha receptor (CHEMBL4680028) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Potent and Selective Human Prostaglandin F (FP) Receptor Antagonist (BAY-6672) for the Treatment of Idiopathic Pulmonary Fibrosis (IPF).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.28 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4643852 | BAY-6672 | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4643852 | BAY-6672 | IC50 | = | 52.0 | nM | 7.28 |