Assay Detail
ADMET
CHEMBL4671909
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Cytotoxicity against human L02 cells assessed as reduction in cell viability after 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | L02 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
HDAC-Bax Multiple Ligands Enhance Bax-Dependent Apoptosis in HeLa Cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.34 | 4.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 4.56 |
| CHEMBL4790235 | — | — | 1 | 4.27 |
| CHEMBL4794290 | — | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | IC50 | = | 27400.0 | nM | 4.56 |
| CHEMBL4790235 | — | IC50 | = | 54200.0 | nM | 4.27 |
| CHEMBL4794290 | — | IC50 | = | 65200.0 | nM | 4.19 |