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Assay Detail

CHEMBL4672886

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Binding
Metal chelating activity assessed as Fe2+-compound complex formation incubated for 5 mins by colorimetry
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Covalent Bridging of Corilagin Improves Antiferroptosis Activity: Comparison with 1,3,6-Tri-O-galloyl-β-d-glucopyranose.
Li X,Liu J,Chen B,Chen Y,Dai W,Li Y,Zhu M
ACS Med Chem Lett (2020) 11 : 2232 -2237
PubMed 33214834 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.99 5.16
Inhibition 2 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL449392 CORILAGIN 2 5.16
CHEMBL389895 2 4.96
CHEMBL1355 SODIUM CITRATE 4.0 1 4.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL449392 CORILAGIN IC50 = 7000.0 nM 5.16
CHEMBL389895 IC50 = 11000.0 nM 4.96
CHEMBL1355 SODIUM CITRATE IC50 = 14000.0 nM 4.85
CHEMBL389895 Inhibition - % -
CHEMBL449392 CORILAGIN Inhibition - % -