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Assay Detail

CHEMBL4672889

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Functional
Antioxidant activity assessed as ferric ion reducing activity using FeCl3.H2O and TPTZ incubated for 30 mins by FRAP assay
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Covalent Bridging of Corilagin Improves Antiferroptosis Activity: Comparison with 1,3,6-Tri-O-galloyl-β-d-glucopyranose.
Li X,Liu J,Chen B,Chen Y,Dai W,Li Y,Zhu M
ACS Med Chem Lett (2020) 11 : 2232 -2237
PubMed 33214834 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.49 4.92
Inhibition 2 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL449392 CORILAGIN 2 4.92
CHEMBL389895 2 4.46
CHEMBL153 TROLOX 1 4.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL449392 CORILAGIN IC50 = 12000.0 nM 4.92
CHEMBL389895 IC50 = 35000.0 nM 4.46
CHEMBL153 TROLOX IC50 = 81000.0 nM 4.09
CHEMBL449392 CORILAGIN Inhibition - % -
CHEMBL389895 Inhibition - % -