Assay Detail
Functional
CHEMBL4673451
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Antimalarial activity against chloroquine sensitive Plasmodium falciparum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An epigrammatic status of the azole-based antimalarial drugs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL157101 | KETOCONAZOLE | 4.0 | 1 | 6.70 |
| CHEMBL104 | CLOTRIMAZOLE | 4.0 | 1 | 6.70 |
| CHEMBL91 | MICONAZOLE | 4.0 | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL157101 | KETOCONAZOLE | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL104 | CLOTRIMAZOLE | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL91 | MICONAZOLE | IC50 | = | 200.0 | nM | 6.70 |