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Assay Detail

CHEMBL4673472

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against chloroquine sensitive Plasmodium falciparum FCR-3 infected in human erythrocytes incubated for 72 hrs by giemsa staining based assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

An epigrammatic status of the azole-based antimalarial drugs
Sharma, Mousmee, Prasher, Parteek
RSC Med Chem (2020) 11 : 184 -211
PubMed 33479627 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 14 8.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL174325 1 8.40
CHEMBL426036 1 8.40
CHEMBL353322 1 8.40
CHEMBL4779036 1 8.40
CHEMBL4763964 1 8.40
CHEMBL174445 1 8.40
CHEMBL4759011 1 8.40
CHEMBL3091932 1 8.40
CHEMBL4749430 1 8.40
CHEMBL4762535 1 8.40
CHEMBL4765178 1 8.40
CHEMBL4759095 1 8.40
CHEMBL4745515 1 8.40
CHEMBL4798664 1 8.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL174325 EC50 = 4.0 nM 8.40
CHEMBL426036 EC50 = 4.0 nM 8.40
CHEMBL353322 EC50 = 4.0 nM 8.40
CHEMBL4779036 EC50 = 4.0 nM 8.40
CHEMBL4763964 EC50 = 4.0 nM 8.40
CHEMBL174445 EC50 = 4.0 nM 8.40
CHEMBL4759011 EC50 = 4.0 nM 8.40
CHEMBL3091932 EC50 = 4.0 nM 8.40
CHEMBL4749430 EC50 = 4.0 nM 8.40
CHEMBL4762535 EC50 = 4.0 nM 8.40
CHEMBL4765178 EC50 = 4.0 nM 8.40
CHEMBL4759095 EC50 = 4.0 nM 8.40
CHEMBL4745515 EC50 = 4.0 nM 8.40
CHEMBL4798664 EC50 = 4.0 nM 8.40