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Assay Detail

CHEMBL4673547

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of LSD1 (unknown origin) expressed in human MGC-803 cells incubated for 5 days by DAPI staining based immunofluorescence method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type MGC-803
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Lysine-specific histone demethylase 1A (CHEMBL6136)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Histone lysine specific demethylase 1 inhibitors
Mehndiratta, Samir, Liou, Jing-Ping
RSC Med Chem (2020) 11 : 969 -981
PubMed 33479691 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL485818 BAICALIN 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL485818 BAICALIN IC50 = 3010.0 nM 5.52