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Assay Detail

CHEMBL4673606

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Modulation of gamma secretase in Wistar rat fetal brain-derived neuronal cell incubated for 3 days by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent developments of small molecule gamma-secretase modulators for Alzheimer''s disease
Mekala, Shekar, Nelson, Grady, Li, Yue-Ming
RSC Med Chem (2020) 11 : 1003 -1022
PubMed 33479693 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.03 7.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1224151 1 7.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1224151 IC50 = 93.0 nM 7.03