Assay Detail
Binding
CHEMBL4673667
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse GOAT expressed in baculovirus infected sf9 insect cell microsomes using biotinylated des-acyl ghrelin and octanoyl-CoA -CoA as substrate incubated for 15 mins by HTRF assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | Sf9 |
| Subcellular | Microsome |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent progress in the discovery of ghrelin O-acyltransferase (GOAT) inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.50 | 8.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4785875 | — | — | 1 | 8.51 |
| CHEMBL4791105 | — | — | 1 | 8.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4785875 | — | IC50 | = | 3.1 | nM | 8.51 |
| CHEMBL4791105 | — | IC50 | = | 3.3 | nM | 8.48 |