Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4673697

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mTOR (unknown origin) by LanthaScreen assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Serine/threonine-protein kinase mTOR (CHEMBL2842)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold
Baillache, Daniel J., Unciti-Broceta, Asier
RSC Med Chem (2020) 11 : 1112 -1135
PubMed 33479617 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.85 8.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3545097 SAPANISERTIB 2.0 1 8.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3545097 SAPANISERTIB Ki = 1.4 nM 8.85