Assay Detail
Binding
CHEMBL4673752
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Inhibition of recombinant Escherichia coli DHFR expressed in Escherichia coli BL21 (DE3) using DiHF as substrate incubated for 5 mins
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification of P218 as a potent inhibitor of Mycobacterium ulcerans DHFR
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 9.70 | 9.70 |
| IC50 | 1 | 10.70 | 10.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL22 | TRIMETHOPRIM | 4.0 | 2 | 10.70 |