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Assay Detail

CHEMBL4673874

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Functional
Antiproliferative activity against human Cal-27 cells by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CAL-27
Confidence 1 — Organism
Curated By Autocuration

Target

CAL-27 (CHEMBL1075408)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances in the discovery of potent and selective HDAC6 inhibitors.
Wang XX,Wan RZ,Liu ZP
Eur J Med Chem (2018) 143 : 1406 -1418
PubMed 29133060 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.69 5.69

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4063658 1 5.69

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4063658 IC50 = 2040.0 nM 5.69