Assay Detail
Binding
CHEMBL4673908
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human HDAC2 using p53 fluorogenic peptide (379 to 382 residues) RHKKAc as substrate by fluorescence-based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in the discovery of potent and selective HDAC6 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.98 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4063658 | — | — | 1 | 6.70 |
| CHEMBL4759780 | — | — | 1 | 5.26 |
| CHEMBL2018302 | TUBASTATIN A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4063658 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL4759780 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL2018302 | TUBASTATIN A | IC50 | > | 30000.0 | nM | - |