Assay Detail
Binding
CHEMBL4674785
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human recombinant PPARgamma by Cheng-Prusoff equation based competitive binding TR-FRET assay
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Kojyl cinnamate esters are peroxisome proliferator-activated receptor α/γ dual agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.58 | 6.40 |
| Activity | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL408 | TROGLITAZONE | 4.0 | 1 | 6.40 |
| CHEMBL4765137 | — | — | 2 | 5.17 |
| CHEMBL4797877 | — | — | 2 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL408 | TROGLITAZONE | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL4765137 | — | Ki | = | 6700.0 | nM | 5.17 |
| CHEMBL4797877 | — | Ki | = | 7000.0 | nM | 5.16 |
| CHEMBL4797877 | — | Activity | - | — | - | |
| CHEMBL4765137 | — | Activity | - | — | - |