Assay Detail
Functional
CHEMBL4674792
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Induction of adipogenesis in human AT-MSC assessed as adiponectin secretion in IDX medium incubated for 5 days by ELISA
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Adipose tissue derived mesenchymal stem cell |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Kojyl cinnamate esters are peroxisome proliferator-activated receptor α/γ dual agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.03 | 6.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL408 | TROGLITAZONE | 4.0 | 1 | 6.07 |
| CHEMBL4797877 | — | — | 1 | 5.12 |
| CHEMBL4765137 | — | — | 1 | 4.83 |
| CHEMBL4740059 | — | — | 1 | 4.69 |
| CHEMBL4796203 | — | — | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL408 | TROGLITAZONE | EC50 | = | 860.0 | nM | 6.07 |
| CHEMBL4797877 | — | EC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL4765137 | — | EC50 | = | 14800.0 | nM | 4.83 |
| CHEMBL4740059 | — | EC50 | = | 20600.0 | nM | 4.69 |
| CHEMBL4796203 | — | EC50 | = | 36600.0 | nM | 4.44 |