Assay Detail
Binding
CHEMBL4675288
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Competitive inhibition of human CSE using varying levels of L-Cys as substrate and fixed PLP levels
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Bioactive Inhibitor with a New Scaffold for Cystathionine γ-Lyase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.77 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275938 | AURINTRICARBOXYLIC ACID | — | 1 | 6.22 |
| CHEMBL4761159 | — | — | 1 | 5.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275938 | AURINTRICARBOXYLIC ACID | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL4761159 | — | Ki | = | 4900.0 | nM | 5.31 |