Assay Detail
Binding
CHEMBL4675296
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CSE using H-Cys as the substrate by tandem well based HTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Bioactive Inhibitor with a New Scaffold for Cystathionine γ-Lyase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.29 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275938 | AURINTRICARBOXYLIC ACID | — | 1 | 5.77 |
| CHEMBL4761159 | — | — | 1 | 5.13 |
| CHEMBL1454910 | NITROXOLINE | 4.0 | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275938 | AURINTRICARBOXYLIC ACID | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL4761159 | — | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL1454910 | NITROXOLINE | IC50 | = | 10700.0 | nM | 4.97 |