Assay Detail
Binding
CHEMBL4676864
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of 125I-alpha-bungarotoxin from rat brain alpha7 nAChR by radioligand binding assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL4980) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Pyridine alkaloids with activity in the central nervous system.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.92 | 6.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1526229 | ANABASINE | — | 1 | 6.41 |
| CHEMBL1496898 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1526229 | ANABASINE | Ki | = | 390.0 | nM | 6.41 |
| CHEMBL1496898 | — | Ki | = | 3700.0 | nM | 5.43 |