Assay Detail
Binding
CHEMBL4677201
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PAX3-FOXO1 (unknown origin) stably transfected Rh4 cells co-expressing CMV-Luc after 24 hrs by SteadyLite luciferase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Rh4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Denigrins and Dactylpyrroles, Arylpyrrole Alkaloids from a Dactylia sp. Marine Sponge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.95 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1554 | DACTINOMYCIN | 4.0 | 1 | 9.00 |
| CHEMBL4747597 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1554 | DACTINOMYCIN | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL4747597 | — | IC50 | = | 13000.0 | nM | 4.89 |