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Assay Detail

CHEMBL4677627

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Escherichia coli HPPK incubated for 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding.
Shi G,Shaw GX,Zhu F,Tarasov SG,Ji X
Bioorg Med Chem (2021) 29 : 115847 -115847
PubMed 33199204 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.36 6.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1928286 1 6.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1928286 IC50 = 440.0 nM 6.36