Assay Detail
Physicochemical
CHEMBL4677668
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Glutathione peroxidase-like catalytic anti-lipid peroxidation activity assessed as inhibition of AAPH-induced lipid peroxidation incubated for 3 hrs in presence of (+/-)-trans-5-Hydroxy-1,2-diselenan-4-yl dodecanoate using soybean lecithin/cholesterol-liposomes by TBARS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Physicochemical |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Glutathione peroxidase-like functions of 1,2-diselenane-4,5-diol and its amphiphilic derivatives: Switchable catalytic cycles depending on peroxide substrates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.73 | 4.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290916 | EDARAVONE | 4.0 | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290916 | EDARAVONE | IC50 | = | 18700.0 | nM | 4.73 |