Assay Detail
Binding
CHEMBL4677783
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to polybromo-1 (3) (unknown origin) by ITC analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 6.07 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4790365 | — | — | 1 | 6.48 |
| CHEMBL4793170 | — | — | 1 | 6.35 |
| CHEMBL4788561 | — | — | 1 | 6.08 |
| CHEMBL4753080 | — | — | 1 | 6.04 |
| CHEMBL4750084 | — | — | 1 | 5.73 |
| CHEMBL4780617 | — | — | 1 | 5.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4790365 | — | Kd | = | 328.0 | nM | 6.48 |
| CHEMBL4793170 | — | Kd | = | 448.0 | nM | 6.35 |
| CHEMBL4788561 | — | Kd | = | 840.0 | nM | 6.08 |
| CHEMBL4753080 | — | Kd | = | 911.0 | nM | 6.04 |
| CHEMBL4750084 | — | Kd | = | 1867.0 | nM | 5.73 |
| CHEMBL4780617 | — | Kd | = | 1963.0 | nM | 5.71 |