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Assay Detail

CHEMBL4678370

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CRAC (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors.
Serafini M,Cordero-Sanchez C,Di Paola R,Bhela IP,Aprile S,Purghè B,Fusco R,Cuzzocrea S,Genazzani AA,Riva B,Pirali T
J Med Chem (2020) 63 : 14761 -14779
PubMed 33253576 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.85 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3403742 1 5.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3403742 IC50 = 1400.0 nM 5.85