Assay Detail
Functional
CHEMBL4681014
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Antiplasmodial activity against drug resistant Plasmodium falciparum V1/S by [3H]hypoxanthine incorporation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.10 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4091762 | CABAMIQUINE | 2.0 | 1 | 9.15 |
| CHEMBL4764214 | — | — | 1 | 9.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4091762 | CABAMIQUINE | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL4764214 | — | EC50 | = | 0.9 | nM | 9.05 |