Assay Detail
Functional
CHEMBL4683346
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against chloroquine-sensitive Plasmodium falciparum F32(CQS)Tanzania incubated for 48 hrs by classical radioactive microdilution method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.09 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3221874 | — | — | 1 | 8.15 |
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 8.15 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3221874 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL269671 | ARTEMISININ | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL76 | CHLOROQUINE | IC50 | = | 11.0 | nM | 7.96 |