Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4683689

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat small intestinal brush border membrane vesicles maltase using sucrose as substrate incubated for 30 mins by glucose oxidase method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Small intestine
Subcellular Vesicle
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes.
Luthra T,Banothu V,Adepally U,Kumar K,M S,Chakrabarti S,Maddi SR,Sen S
Eur J Med Chem (2020) 188 : 112034 -112034
PubMed 31927314 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.75 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4745678 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4745678 IC50 = 180.0 nM 6.75