Assay Detail
Functional
CHEMBL4686887
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Antiproliferative activity against human A 172 cells measured after 7 days by CCK8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A 172 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of new LXRβ agonists as glioblastoma inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.15 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4797369 | — | — | 1 | 5.22 |
| CHEMBL456237 | LXR-623 | 1.0 | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4797369 | — | IC50 | = | 6030.0 | nM | 5.22 |
| CHEMBL456237 | LXR-623 | IC50 | = | 8300.0 | nM | 5.08 |